Pigs receiving cortisol showed strongly decreased adaptive immune cell numbers and increased neutrophils, accompanied by hampered lymphocyte proliferation but increased monocyte phagocytosis. ![]() Total IgG and IgM Ab levels were determined via ELISA. Immune cell numbers and phagocytic activity were evaluated by flow cytometry and lymphocyte proliferation by 3H-thymidine incorporation. Blood samples were collected before treatment (−24 h, −22 h, 0 h), during treatment (+2 h, +24 h, +48 h), and at 72 h postinfusion. Castrated male pigs ( n = 34) were treated with physiological doses of either adrenaline, noradrenaline, or cortisol via i.v. ![]() Therefore, the aim of this study was to examine the in vivo effects of adrenaline, noradrenaline, and cortisol on number and functionality of porcine blood immune cells. Exceptionally little is known about the effects of catecholamines. ![]() Despite the importance of pigs ( Sus scrofa domestica) in livestock production and their increasing role as a model organism for human physiology, knowledge about the porcine immune system under the influence of stress hormones is fragmentary.
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